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Fred Ehrsam and Brian Armstrong started Coinbase in a two-bedroom apartment thirteen years ago. Both men are now billionaires, but Ehrsam has quietly parlayed his fortunes into neuroscience innovation, launching a brain interface startup in 2024 called Nudge. On Monday, the firm unveiled its first product, the Nudge Zero, a non-invasive ultrasound neuromodulation device. That’s a mouthful, but “non-invasive ultrasound neuromodulation” simply means modifying brain activity by using an ultrasound machine. Such a device emits ultrasound waves that impact cell membranes in the brain without causing permanent changes or damage. (The “Nudge Zero” is the first device from Fred Ehrsam’s neuroscience startup / Nudge on X) Reasons for using ultrasound neuromodulation devices vary, but they typically fall into two overlapping categories, medical and therapeutic. Medical issues would include neurological conditions such as epilepsy and pain management, while therapeutic conditions would encompass less acute scenarios such as depression. The Nudge Zero, according to Ehrsam, will first tackle acute medical conditions, and its predecessor will eventually be introduced as a therapeutic solution for individuals seeking various forms of mental well-being. “We will first use the device to attempt to treat acute medical conditions in the coming months,” Ehrsam explained. “With the eventual goal of creating a headphone-like miniaturized version … to enhance mood, cognition, and daily life for healthy people.” (Computer renderings of what Nudge’s therapeutic wearables may look like once launched / Nudge on X) Prior to launching Nudge in 2024, Ehrsam and Sequioa veteran Matt Huang co-founded Paradigm in 2018, a crypto-focused venture capital firm that manages three funds, the most recent of which closed at $850 million last June. The 36-year-old Ehrsam, now worth $2.1 billion, according to Forbes, stepped away from his managing partner role at the firm in 2023 but has remained at Paradigm as a general partner. It appears neuroscience and not crypto is now his primary focus. “We believe improving the human experience is the most important thing to work on. This should be the goal of technology,” Ehrsam said. “And building technologies to interface with the brain is the most direct way of doing so.” 免责声明：本文章仅代表作者个人观点，不代表本平台的立场和观点。本文章仅供信息分享，不构成对任何人的任何投资建议。用户与作者之间的任何争议，与本平台无关。如网页中刊载的文章或图片涉及侵权，请提供相关的权利证明和身份证明发送邮件到[email protected]，本平台相关工作人员将会进行核查。

Billionaire Bill Ackman has urged the Trump administration to be prudent in its attempt to change the current trading system, which he says has served the United States well. Ackman warned against pursuing a course that upends the world order in a way that “disadvantages our country over the long term.” Instead of the “reciprocal” tariffs that the U.S. has imposed, Ackman said he favors a 10% across-the-board tariff. He characterized this as compensation due to the U.S. for the “historically unfair trade practices that have contributed to our massive deficits and national debt.” He also proposed, without specifying, keeping “pressure on China to resolve materially unfair trading practices, IP theft, and currency manipulation.” The billionaire’s comments came a day after he was quoted warning of an “economic nuclear winter” for the U.S. if Trump’s reciprocal tariffs were not paused. Ackman, who backed Trump in the last U.S. election, argued that a three-month pause would allow the United States to negotiate better deals with its trade partners. Like other U.S. billionaire backers of Trump, Ackman believes the U.S. government’s current course could spell disaster for the country. While the U.S. President has since dismissed rumors he was contemplating a pause as fake news, some observers believe these reports helped limit losses on U.S. markets on April 7, the so-called Black Monday. However, in his X post reiterating his call for a 90-day pause, Ackman expanded on why the Trump administration needs rethink its current policy. “It does not make sense to have balanced trade with countries that are smaller than us and that have fewer resources to spend on U.S. goods, i.e., we will forever be buying more from Madagascar than they will buy from us,” Ackman argued. He also repeated the argument that the manufacturing jobs that Trump wants to return to the United States are not needed. Ackman also implied that the calculations used by the Trump administration to determine the reciprocal tariffs to be levied exclude U.S. exports such as software, intellectual property, and finance. He asserted that the inclusion of these exports would “make the balance of trade statistics look much more balanced.” Ackman also took aim at the Trump administration’s insistence on comparing the U.S., which has a larger economy and higher standard of living, with smaller and less developed countries. “A goal of generating a dollar of exports for every dollar of imports is not a useful one, particularly on a country-by-country basis in light of our massively higher standard of living and having the largest economy in the world,” the billionaire said. 免责声明：本文章仅代表作者个人观点，不代表本平台的立场和观点。本文章仅供信息分享，不构成对任何人的任何投资建议。用户与作者之间的任何争议，与本平台无关。如网页中刊载的文章或图片涉及侵权，请提供相关的权利证明和身份证明发送邮件到[email protected]，本平台相关工作人员将会进行核查。

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